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Molecular perturbation strategies to examine spatiotemporal features of Rho GEF and Rho GTPase activity in living cells

Much of our current knowledge of Rho GTPase networks and the regulation by Rho guanine exchange factors (Rho GEFs) and Rho GTPase activating proteins (Rho GAPs) is based on population-based techniques. Over the last decades, technologies that enable single cell analysis with high spatial and tempora...

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Detalles Bibliográficos
Autores principales: Goedhart, Joachim, van Unen, Jakobus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548299/
https://www.ncbi.nlm.nih.gov/pubmed/28521592
http://dx.doi.org/10.1080/21541248.2017.1302551