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Molecular perturbation strategies to examine spatiotemporal features of Rho GEF and Rho GTPase activity in living cells
Much of our current knowledge of Rho GTPase networks and the regulation by Rho guanine exchange factors (Rho GEFs) and Rho GTPase activating proteins (Rho GAPs) is based on population-based techniques. Over the last decades, technologies that enable single cell analysis with high spatial and tempora...
Autores principales: | Goedhart, Joachim, van Unen, Jakobus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548299/ https://www.ncbi.nlm.nih.gov/pubmed/28521592 http://dx.doi.org/10.1080/21541248.2017.1302551 |
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