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Strength of T cell signaling regulates HIV-1 replication and establishment of latency

A major barrier to curing HIV-1 is the long-lived latent reservoir that supports re-emergence of HIV-1 upon treatment interruption. Targeting this reservoir will require mechanistic insights into the establishment and maintenance of HIV-1 latency. Whether T cell signaling at the time of HIV-1 infect...

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Detalles Bibliográficos
Autores principales:	Gagne, Matthew, Michaels, Daniel, Schiralli Lester, Gillian M., Gummuluru, Suryaram, Wong, Wilson W., Henderson, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548398/ https://www.ncbi.nlm.nih.gov/pubmed/31116788 http://dx.doi.org/10.1371/journal.ppat.1007802

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