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ZAP’s stress granule localization is correlated with its antiviral activity and induced by virus replication
Cellular antiviral programs encode molecules capable of targeting multiple steps in the virus lifecycle. Zinc-finger antiviral protein (ZAP) is a central and general regulator of antiviral activity that targets pathogen mRNA stability and translation. ZAP is diffusely cytoplasmic, but upon infection...
Autores principales: | Law, Lok Man John, Razooky, Brandon S., Li, Melody M. H., You, Shihyun, Jurado, Andrea, Rice, Charles M., MacDonald, Margaret R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548403/ https://www.ncbi.nlm.nih.gov/pubmed/31116799 http://dx.doi.org/10.1371/journal.ppat.1007798 |
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