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Sp3-cificity of TNF-α expression promotes the Smac mimetic-mediated killing of cancer cells
A genome-wide small-interfering RNA-based screen identified the transcription factor Specificity Protein 3 (SP3) as a critical factor for Second mitochondrial-derived activator of caspase (Smac) mimetic-mediated killing of cancer cells. In concert with Nuclear Factor kappa B (NF-κB,) SP3 is required...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548490/ https://www.ncbi.nlm.nih.gov/pubmed/31211235 http://dx.doi.org/10.1080/23723556.2019.1607456 |