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T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function
Innate lymphoid cells (ILCs) play an important role in regulating immune responses at mucosal surfaces. The transcription factor T-bet is crucial for the function of ILC1s and NCR(+) ILC3s and constitutive deletion of T-bet prevents the development of these subsets. Lack of T-bet in the absence of a...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548562/ https://www.ncbi.nlm.nih.gov/pubmed/30356098 http://dx.doi.org/10.1038/s41385-018-0092-6 |