T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function

Innate lymphoid cells (ILCs) play an important role in regulating immune responses at mucosal surfaces. The transcription factor T-bet is crucial for the function of ILC1s and NCR(+) ILC3s and constitutive deletion of T-bet prevents the development of these subsets. Lack of T-bet in the absence of a...

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Detalles Bibliográficos
Autores principales: Garrido-Mesa, N., Schroeder, J-H., Stolarczyk, E., Gallagher, A. L., Lo, J. W., Bailey, C., Campbell, L., Sexl, V., MacDonald, T. T., Howard, J. K., Grencis, R. K., Powell, N., Lord, G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548562/
https://www.ncbi.nlm.nih.gov/pubmed/30356098
http://dx.doi.org/10.1038/s41385-018-0092-6

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