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Enhanced Intranasal Absorption of Naltrexone by Dodecyl Maltopyranoside: Implications for the Treatment of Opioid Overdose

Based on its high affinity for μ opiate receptors and reported half‐life after oral administration, the pharmacokinetic properties of intranasal naltrexone were examined to evaluate its potential to treat opioid overdose. This study was prompted by the marked rise in overdose deaths linked to synthe...

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Detalles Bibliográficos
Autores principales: Krieter, Philip, Gyaw, Shwe, Chiang, C. Nora, Crystal, Roger, Skolnick, Phil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548568/
https://www.ncbi.nlm.nih.gov/pubmed/30698833
http://dx.doi.org/10.1002/jcph.1384

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