Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups

Categorizing people with late-onset Alzheimer’s disease into biologically coherent subgroups is important for personalized medicine. We evaluated data from five studies (total n = 4050, of whom 2431 had genome-wide single-nucleotide polymorphism (SNP) data). We assigned people to cognitively defined...

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Detalles Bibliográficos
Autores principales: Mukherjee, Shubhabrata, Mez, Jesse, Trittschuh, Emily H., Saykin, Andrew J., Gibbons, Laura E., Fardo, David W., Wessels, Madeline, Bauman, Julianna, Moore, Mackenzie, Choi, Seo-Eun, Gross, Alden L., Rich, Joanne, Louden, Diana K. N., Sanders, R. Elizabeth, Grabowski, Thomas J., Bird, Thomas D., McCurry, Susan M., Snitz, Beth E., Kamboh, M. Ilyas, Lopez, Oscar L., De Jager, Philip L., Bennett, David A., Keene, C. Dirk, Larson, Eric B., Crane, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548676/
https://www.ncbi.nlm.nih.gov/pubmed/30514930
http://dx.doi.org/10.1038/s41380-018-0298-8

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