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Inhibition of PP2A activity by H(2)O(2) during mitosis disrupts nuclear envelope reassembly and alters nuclear shape
Many types of cancer cells exhibit abnormal nuclear shapes induced by various molecular changes. However, whether reactive oxygen species (ROS) induce nuclear deformation has not been fully addressed. Here, we show that hydrogen peroxide (H(2)O(2)) treatment induced concentration-dependent alteratio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548778/ https://www.ncbi.nlm.nih.gov/pubmed/31164634 http://dx.doi.org/10.1038/s12276-019-0260-0 |