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Whole-Body ARHGAP21-Deficiency Improves Energetic Homeostasis in Lean and Obese Mice
Inhibition of Rab-GAP TBC1 domain family member 1 (TBC1D1) reduces body weight and increases energy expenditure in mice. Here, we assessed the possible involvement of GTPase activating protein 21 (ARHGAP21), a Rho-GAP protein, in energy homeostasis. Wild-type and whole-body ARHGAP21-haplodeficient m...
Autores principales: | Soares, Gabriela Moreira, Zangerolamo, Lucas, Costa-Júnior, Jose Maria, Vettorazzi, Jean Franciesco, Carneiro, Everardo Magalhães, Saad, Sara Teresinha, Boschero, Antonio Carlos, Barbosa-Sampaio, Helena Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548804/ https://www.ncbi.nlm.nih.gov/pubmed/31191459 http://dx.doi.org/10.3389/fendo.2019.00338 |
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