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F8 Inversions at Xq28 Causing Hemophilia A Are Associated With Specific Methylation Changes: Implication for Molecular Epigenetic Diagnosis

Diverse DNA structural variations (SVs) in human cancers and several other diseases are well documented. For genomic inversions in particular, the disease causing mechanism may not be clear, especially if the inversion border does not cross a coding sequence. Understanding about the molecular proces...

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Detalles Bibliográficos
Autores principales:	Jamil, Muhammad Ahmer, Sharma, Amit, Nuesgen, Nicole, Pezeshkpoor, Behnaz, Heimbach, André, Pavlova, Anne, Oldenburg, Johannes, El-Maarri, Osman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548806/ https://www.ncbi.nlm.nih.gov/pubmed/31191618 http://dx.doi.org/10.3389/fgene.2019.00508

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