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Human Monocyte-Derived Dendritic Cells Produce Millimolar Concentrations of ROS in Phagosomes Per Second
Neutrophils kill ingested pathogens by the so-called oxidative burst, where reactive oxygen species (ROS) are produced in the lumen of phagosomes at very high rates (mM/s), although these rates can only be maintained for a short period (minutes). In contrast, dendritic cells produce ROS at much lowe...
Autores principales: | Paardekooper, Laurent M., Dingjan, Ilse, Linders, Peter T. A., Staal, Alexander H. J., Cristescu, Simona M., Verberk, Wilco C. E. P., van den Bogaart, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548834/ https://www.ncbi.nlm.nih.gov/pubmed/31191556 http://dx.doi.org/10.3389/fimmu.2019.01216 |
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