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Targeting Heparanase in Cancer: Inhibition by Synthetic, Chemically Modified, and Natural Compounds

Heparanase is an endoglycosidase involved in remodeling the extracellular matrix and thereby in regulating multiple cellular processes and biological activities. It cleaves heparan sulfate (HS) side chains of HS proteoglycans into smaller fragments and hence regulates tissue morphogenesis, different...

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Detalles Bibliográficos
Autores principales:	Mohan, Chakrabhavi Dhananjaya, Hari, Swetha, Preetham, Habbanakuppe D., Rangappa, Shobith, Barash, Uri, Ilan, Neta, Nayak, S. Chandra, Gupta, Vijai K., Basappa, Vlodavsky, Israel, Rangappa, Kanchugarakoppal S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548846/ https://www.ncbi.nlm.nih.gov/pubmed/31103854 http://dx.doi.org/10.1016/j.isci.2019.04.034

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