Cargando…

Role of Myeloid-Epithelial-Reproductive Tyrosine Kinase and Macrophage Polarization in the Progression of Atherosclerotic Lesions Associated With Nonalcoholic Fatty Liver Disease

Recent lines of evidence highlight the involvement of myeloid-epithelial-reproductive tyrosine kinase (MerTK) in metabolic disease associated with liver damage. MerTK is mainly expressed in anti-inflammatory M2 macrophages where it mediates transcriptional changes including suppression of proinflamm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pastore, Mirella, Grimaudo, Stefania, Pipitone, Rosaria Maria, Lori, Giulia, Raggi, Chiara, Petta, Salvatore, Marra, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548874/ https://www.ncbi.nlm.nih.gov/pubmed/31191323 http://dx.doi.org/10.3389/fphar.2019.00604

Ejemplares similares

A Genetic and Metabolic Staging System for Predicting the Outcome of Nonalcoholic Fatty Liver Disease
por: Pennisi, Grazia, et al.
Publicado: (2022)

Mer Tyrosine Kinase (MERTK) modulates liver fibrosis progression and hepatocellular carcinoma development
por: Pipitone, Rosaria Maria, et al.
Publicado: (2022)

MAFLD: a multisystem disease
por: Pipitone, Rosaria Maria, et al.
Publicado: (2023)

Glucokinase Regulatory Protein Gene Polymorphism Affects Liver Fibrosis in Non-Alcoholic Fatty Liver Disease
por: Petta, Salvatore, et al.
Publicado: (2014)

Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver
por: Dongiovanni, P., et al.
Publicado: (2017)

Role of Chemokines in the Biology of Cholangiocarcinoma
por: Caligiuri, Alessandra, et al.
Publicado: (2020)

Multifaceted Aspects of Metabolic Plasticity in Human Cholangiocarcinoma: An Overview of Current Perspectives
por: Pastore, Mirella, et al.
Publicado: (2020)

The Role of Stroma in Cholangiocarcinoma: The Intriguing Interplay between Fibroblastic Component, Immune Cell Subsets and Tumor Epithelium
por: Gentilini, Alessandra, et al.
Publicado: (2018)

PNPLA3 GG Genotype and Carotid Atherosclerosis in Patients with Non-Alcoholic Fatty Liver Disease
por: Petta, Salvatore, et al.
Publicado: (2013)

Evaluation of atherosclerotic findings in patients with nonalcoholic fatty liver disease
por: Mohammadi, Afshin, et al.
Publicado: (2011)

The interplay between nonalcoholic fatty liver disease and atherosclerotic cardiovascular disease
por: Finney, Alexandra C., et al.
Publicado: (2023)

Macrophage MerTK promotes profibrogenic cross-talk with hepatic stellate cells via soluble mediators
por: Pastore, Mirella, et al.
Publicado: (2022)

Protein phosphatase 1 regulatory subunit 3B gene variation protects against hepatic fat accumulation and fibrosis in individuals at high risk of nonalcoholic fatty liver disease
por: Dongiovanni, Paola, et al.
Publicado: (2018)

Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease
por: Donati, Benedetta, et al.
Publicado: (2017)

Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD
por: Di Mauro, Stefania, et al.
Publicado: (2021)

Regulation of Human Macrophage M1–M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1
por: Raggi, Federica, et al.
Publicado: (2017)

Mortality Risk Detected by Atherosclerotic Cardiovascular Disease Score in Patients With Nonalcoholic Fatty Liver Disease
por: Golabi, Pegah, et al.
Publicado: (2019)

Serum coding and non‐coding RNAs as biomarkers of NAFLD and fibrosis severity
por: Di Mauro, Stefania, et al.
Publicado: (2019)

Nonalcoholic fatty liver disease and diabetes
por: Bellini, Maria Irene, et al.
Publicado: (2022)

Tyrosine levels are associated with insulin resistance in patients with nonalcoholic fatty liver disease
por: Kawanaka, Miwa, et al.
Publicado: (2015)

Curcumin and Andrographolide Co-Administration Safely Prevent Steatosis Induction and ROS Production in HepG2 Cell Line
por: Pipitone, Rosaria Maria, et al.
Publicado: (2023)

Nonalcoholic Fatty Liver Disease as an Emerging Risk Factor and Potential Intervention Target for Atherosclerotic Cardiovascular Diseases
por: Zhang, Daqing, et al.
Publicado: (2023)

A Natural-Like Synthetic Small Molecule Impairs Bcr-Abl Signaling Cascades and Induces Megakaryocyte Differentiation in Erythroleukemia Cells
por: Turroni, Silvia, et al.
Publicado: (2013)

SARS-CoV-2 Viral Load, IFNλ Polymorphisms and the Course of COVID-19: An Observational Study
por: Amodio, Emanuele, et al.
Publicado: (2020)

PNPLA3 and TLL-1 Polymorphisms as Potential Predictors of Disease Severity in Patients With COVID-19
por: Grimaudo, Stefania, et al.
Publicado: (2021)

Red and golden tomato administration improves fat diet-induced hepatic steatosis in rats by modulating HNF4α, Lepr, and GK expression
por: Pipitone, Rosaria Maria, et al.
Publicado: (2023)

Fibroblast Growth Factor 21 is Related to Atherosclerosis Independent of Nonalcoholic Fatty Liver Disease and Predicts Atherosclerotic Cardiovascular Events
por: Wu, Liang, et al.
Publicado: (2020)

Myeloid-specific blockade of Notch signaling ameliorates nonalcoholic fatty liver disease in mice
por: Ding, Jian, et al.
Publicado: (2023)

Renin-Angiotensin System Inhibitors, Type 2 Diabetes and Fibrosis Progression: An Observational Study in Patients with Nonalcoholic Fatty Liver Disease
por: Pelusi, Serena, et al.
Publicado: (2016)

Liver stiffness quantification in biopsy-proven nonalcoholic fatty liver disease patients using shear wave elastography in comparison with transient elastography
por: Taibbi, Adele, et al.
Publicado: (2021)

Macrophage polarization and acceleration of atherosclerotic plaques in a swine model
por: Lee, Seul-Gee, et al.
Publicado: (2018)

The Presence of White Matter Lesions Is Associated With the Fibrosis Severity of Nonalcoholic Fatty Liver Disease
por: Petta, Salvatore, et al.
Publicado: (2016)

Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease
por: Pelusi, Serena, et al.
Publicado: (2019)

Mucosal-Associated Invariant T Cells Improve Nonalcoholic Fatty Liver Disease Through Regulating Macrophage Polarization
por: Li, Yanmei, et al.
Publicado: (2018)

The OMICs Window into Nonalcoholic Fatty Liver Disease (NAFLD)
por: Carulli, Lucia, et al.
Publicado: (2019)

Vitamin D and macrophage polarization in epicardial adipose tissue of atherosclerotic swine
por: Gunasekar, Palanikumar, et al.
Publicado: (2018)

The “Janus” Role of C/EBPs Family Members in Cancer Progression
por: Tolomeo, Manlio, et al.
Publicado: (2020)

Advances in paediatric nonalcoholic fatty liver disease: Role of lipidomics
por: Di Sessa, Anna, et al.
Publicado: (2021)

Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
por: Imajo, Kento, et al.
Publicado: (2013)

Spleen tyrosine kinase inhibition restores myeloid homeostasis in COVID-19
por: Wigerblad, Gustaf, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_g8p604t0tj5pk53eft99enlfup