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Cationic micelle-based siRNA delivery for efficient colon cancer gene therapy

Small interfering RNA (siRNA)-based gene therapy has provided an alternative strategy for cancer therapy. One of the key components within gene therapy process is the delivery system. As a novel non-viral gene vector, DMP, prepared by modifying mPEG-PCL micelle with cationic DOTAP lipid, has been pr...

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Detalles Bibliográficos
Autores principales: Lu, Yongping, Zhong, Lei, Jiang, Zhongliang, Pan, Haixia, Zhang, Yuanfa, Zhu, Guonian, Bai, Lan, Tong, Rongsheng, Shi, Jianyou, Duan, Xingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548891/
https://www.ncbi.nlm.nih.gov/pubmed/31165329
http://dx.doi.org/10.1186/s11671-019-2985-z