Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects

BACKGROUND: Metformin, the most widely administered diabetes drug, has been proposed as a candidate adjunctive host-directed therapy for tuberculosis, but little is known about its effects on human host responses to Mycobacterium tuberculosis. METHODS: We investigated in vitro and in vivo effects of...

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Detalles Bibliográficos
Autores principales: Lachmandas, Ekta, Eckold, Clare, Böhme, Julia, Koeken, Valerie A C M, Marzuki, Mardiana Binte, Blok, Bastiaan, Arts, Rob J W, Chen, Jinmiao, Teng, Karen W W, Ratter, Jacqueline, Smolders, Elise J, Van den Heuvel, Corina, Stienstra, Rinke, Dockrell, Hazel M, Newell, Evan, Netea, Mihai G, Singhal, Amit, Cliff, Jacqueline M, Van Crevel, Reinout
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548897/
https://www.ncbi.nlm.nih.gov/pubmed/30753544
http://dx.doi.org/10.1093/infdis/jiz064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548897/
https://www.ncbi.nlm.nih.gov/pubmed/30753544
http://dx.doi.org/10.1093/infdis/jiz064

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