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Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects
BACKGROUND: Metformin, the most widely administered diabetes drug, has been proposed as a candidate adjunctive host-directed therapy for tuberculosis, but little is known about its effects on human host responses to Mycobacterium tuberculosis. METHODS: We investigated in vitro and in vivo effects of...
Autores principales: | Lachmandas, Ekta, Eckold, Clare, Böhme, Julia, Koeken, Valerie A C M, Marzuki, Mardiana Binte, Blok, Bastiaan, Arts, Rob J W, Chen, Jinmiao, Teng, Karen W W, Ratter, Jacqueline, Smolders, Elise J, Van den Heuvel, Corina, Stienstra, Rinke, Dockrell, Hazel M, Newell, Evan, Netea, Mihai G, Singhal, Amit, Cliff, Jacqueline M, Van Crevel, Reinout |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548897/ https://www.ncbi.nlm.nih.gov/pubmed/30753544 http://dx.doi.org/10.1093/infdis/jiz064 |
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