An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis

Brain granuloma occurs under certain conditions. Herpes simplex virus (HSV) causes granulomatous encephalitis in children; however, it has been rarely reported in adults. A 74-year-old man with a history of herpes simplex encephalitis suffered recurrent seizures. Brain magnetic resonance imaging rev...

Descripción completa

Detalles Bibliográficos
Autores principales: Iwai, Yuta, Nishimura, Kazutaka, Fukushima, Takeshi, Ito, Takashi, Watanabe, Yoshiyuki, Noro, Masahiro, Kuwabara, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548933/
https://www.ncbi.nlm.nih.gov/pubmed/30626834
http://dx.doi.org/10.2169/internalmedicine.2046-18
_version_ 1783423902639194112
author Iwai, Yuta
Nishimura, Kazutaka
Fukushima, Takeshi
Ito, Takashi
Watanabe, Yoshiyuki
Noro, Masahiro
Kuwabara, Satoshi
author_facet Iwai, Yuta
Nishimura, Kazutaka
Fukushima, Takeshi
Ito, Takashi
Watanabe, Yoshiyuki
Noro, Masahiro
Kuwabara, Satoshi
author_sort Iwai, Yuta
collection PubMed
description Brain granuloma occurs under certain conditions. Herpes simplex virus (HSV) causes granulomatous encephalitis in children; however, it has been rarely reported in adults. A 74-year-old man with a history of herpes simplex encephalitis suffered recurrent seizures. Brain magnetic resonance imaging revealed a mass lesion and resection was performed. A polymerase chain reaction using a brain biopsy specimen was positive for HSV DNA; thus, the patient was diagnosed with HSV-associated granulomatous encephalitis. After administering acyclovir, the patient showed improvement. HSV can cause granulomatous encephalitis in adults, and acyclovir can be used for its treatment.
format Online
Article
Text
id pubmed-6548933
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-65489332019-06-17 An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis Iwai, Yuta Nishimura, Kazutaka Fukushima, Takeshi Ito, Takashi Watanabe, Yoshiyuki Noro, Masahiro Kuwabara, Satoshi Intern Med Case Report Brain granuloma occurs under certain conditions. Herpes simplex virus (HSV) causes granulomatous encephalitis in children; however, it has been rarely reported in adults. A 74-year-old man with a history of herpes simplex encephalitis suffered recurrent seizures. Brain magnetic resonance imaging revealed a mass lesion and resection was performed. A polymerase chain reaction using a brain biopsy specimen was positive for HSV DNA; thus, the patient was diagnosed with HSV-associated granulomatous encephalitis. After administering acyclovir, the patient showed improvement. HSV can cause granulomatous encephalitis in adults, and acyclovir can be used for its treatment. The Japanese Society of Internal Medicine 2019-01-10 2019-05-15 /pmc/articles/PMC6548933/ /pubmed/30626834 http://dx.doi.org/10.2169/internalmedicine.2046-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Iwai, Yuta
Nishimura, Kazutaka
Fukushima, Takeshi
Ito, Takashi
Watanabe, Yoshiyuki
Noro, Masahiro
Kuwabara, Satoshi
An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis
title An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis
title_full An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis
title_fullStr An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis
title_full_unstemmed An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis
title_short An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis
title_sort adult case of herpes simplex virus-associated granulomatous encephalitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548933/
https://www.ncbi.nlm.nih.gov/pubmed/30626834
http://dx.doi.org/10.2169/internalmedicine.2046-18
work_keys_str_mv AT iwaiyuta anadultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT nishimurakazutaka anadultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT fukushimatakeshi anadultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT itotakashi anadultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT watanabeyoshiyuki anadultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT noromasahiro anadultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT kuwabarasatoshi anadultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT iwaiyuta adultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT nishimurakazutaka adultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT fukushimatakeshi adultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT itotakashi adultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT watanabeyoshiyuki adultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT noromasahiro adultcaseofherpessimplexvirusassociatedgranulomatousencephalitis
AT kuwabarasatoshi adultcaseofherpessimplexvirusassociatedgranulomatousencephalitis

Ejemplares similares