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A Genomic, Evolutionary, and Mechanistic Study of MCR‐5 Action Suggests Functional Unification across the MCR Family of Colistin Resistance
A growing number of mobile colistin resistance (MCR) proteins is threatening the renewed interest of colistin as a “last‐resort” defense against carbapenem‐resistant pathogens. Here, the comparative genomics of a large plasmid harboring mcr‐5 from Aeromonas hydrophila and the structural/functional p...
Autores principales: | Zhang, Huimin, Zong, Zhiyong, Lei, Sheng, Srinivas, Swaminath, Sun, Jian, Feng, Yu, Huang, Man, Feng, Youjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548960/ https://www.ncbi.nlm.nih.gov/pubmed/31179217 http://dx.doi.org/10.1002/advs.201900034 |
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