Cargando…

Tranilast enhances the effect of anticancer agents in osteosarcoma

Tranilast [N-(3′,4′-dimethoxycinnamoyl)-anthranilic acid], initially developed as an antiallergic drug, also exhibits a growth inhibitory effect on various types of cancer. Osteosarcoma is treated mainly with high-dose methotrexate, doxorubicin, cisplatin and ifosfamide; however, 20–30 % of patients...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakashima, Takayuki, Nagano, Satoshi, Setoguchi, Takao, Sasaki, Hiromi, Saitoh, Yoshinobu, Maeda, Shingo, Komiya, Setsuro, Taniguchi, Noboru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549073/ https://www.ncbi.nlm.nih.gov/pubmed/31059083 http://dx.doi.org/10.3892/or.2019.7150

Ejemplares similares

Validation of Different Nutritional Assessment Tools in Predicting Prognosis of Patients with Soft Tissue Spindle-Cell Sarcomas
por: Sasaki, Hiromi, et al.
Publicado: (2018)

TGF-β Promotes the Proliferation of Microglia In Vitro
por: Bureta, Costansia, et al.
Publicado: (2019)

Smoothened as a new therapeutic target for human osteosarcoma
por: Hirotsu, Masataka, et al.
Publicado: (2010)

Differentiation of lipoma and atypical lipomatous tumor by a scoring system: implication of increased vascularity on pathogenesis of liposarcoma
por: Nagano, Satoshi, et al.
Publicado: (2015)

Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index
por: Sasaki, Hiromi, et al.
Publicado: (2018)

Suppression of Osteosarcoma Cell Invasion by Chemotherapy Is Mediated by Urokinase Plasminogen Activator Activity via Up-Regulation of EGR1
por: Matsunoshita, Yukihiro, et al.
Publicado: (2011)

Osteoarthritis of the hip joint in elderly patients is most commonly atrophic, with low parameters of acetabular dysplasia and possible involvement of osteoporosis
por: Ishidou, Yasuhiro, et al.
Publicado: (2017)

Computer-assisted quantitative evaluation of bisphosphonate treatment for Paget's disease of bone using the bone scan index
por: Nagano, Satoshi, et al.
Publicado: (2016)

Metastasis of osteosarcoma to the trapezius muscle: a case report
por: Sakamoto, Yuichiro, et al.
Publicado: (2014)

Intraoperative evaluation of polymorphonuclear leukocyte during second-stage revision surgery promote overdiagnosis of persistent periprosthetic joint infection
por: Saitoh, Yoshinobu, et al.
Publicado: (2018)

Arsenic Trioxide Prevents Osteosarcoma Growth by Inhibition of GLI Transcription via DNA Damage Accumulation
por: Nakamura, Shunsuke, et al.
Publicado: (2013)

Doppler ultrasound for diagnosis of soft tissue sarcoma: efficacy of ultrasound-based screening score
por: Nagano, Satoshi, et al.
Publicado: (2015)

Diagnosing and discriminating between primary and secondary aneurysmal bone cysts
por: Sasaki, Hiromi, et al.
Publicado: (2017)

Hypertrophic spinal pachymeningitis associated with human T-cell lymphotrophic virus-1 infection and Sjogren’s syndrome: A case report and brief literature review
por: Bureta, Costansia A., et al.
Publicado: (2018)

Finite element analysis of cementless femoral stems based on mid- and long-term radiological evaluation
por: Matsuyama, Kanehiro, et al.
Publicado: (2016)

Giant cell tumor of the clavicle: report of a case in a rare location with consideration of surgical method
por: Nagano, Satoshi, et al.
Publicado: (2015)

Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report
por: Tanaka, Motoyuki, et al.
Publicado: (2012)

RBPJ Is a Novel Target for Rhabdomyosarcoma Therapy
por: Nagao, Hiroko, et al.
Publicado: (2012)

TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells
por: Shinohara, Naohiro, et al.
Publicado: (2017)

Analysis of Surgical Site Infection after Musculoskeletal Tumor Surgery: Risk Assessment Using a New Scoring System
por: Nagano, Satoshi, et al.
Publicado: (2014)

Clinical outcomes of arthroscopic rotator cuff repair: a retrospective comparison of double-layer, double-row and suture bridge methods
por: Kakoi, Hironori, et al.
Publicado: (2018)

Early Complete Remission of Osteoid Osteoma with Conservative Medical Management
por: Yokouchi, Masahiro, et al.
Publicado: (2014)

Extended curettage and heat ablation for desmoplastic fibroma of the distal femur with a 12-year follow-up period: A case report
por: YOKOUCHI, MASAHIRO, et al.
Publicado: (2014)

Castleman’s disease in the retroperitoneal space mimicking a paraspinal schwannoma: a case report
por: Nagano, Satoshi, et al.
Publicado: (2013)

Endemic impact of human T cell leukemia virus type 1 screening in bone allografts
por: Ishidou, Yasuhiro, et al.
Publicado: (2016)

Risk factors for unavoidable removal of instrumentation after surgical site infection of spine surgery: A retrospective case-control study
por: Tominaga, Hiroyuki, et al.
Publicado: (2016)

Risk factors for bone loss in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs
por: Tawaratsumida, Hiroki, et al.
Publicado: (2017)

Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression
por: Tsuru, A, et al.
Publicado: (2015)

Uricosuric targets of tranilast
por: Mandal, Asim K., et al.
Publicado: (2017)

Reconstruction of injured spinal cord by epigenetic regulation of transplanted neural stem cells
por: Abematsu, Masahiko, et al.
Publicado: (2012)

Risk Factors for Venous Thromboembolism After Spine Surgery
por: Tominaga, Hiroyuki, et al.
Publicado: (2015)

Cut-off values of latent infection in patients with rapid migration following bipolar hip hemiarthroplasty
por: Setoguchi, Takao, et al.
Publicado: (2016)

Lumbar spine epidural abscess and facet joint septic arthritis due to Streptococcus agalactiae: a case report
por: Bureta, Costansia, et al.
Publicado: (2018)

BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts
por: Yahiro, Yuhei, et al.
Publicado: (2020)

Enrichment of bacteria samples by centrifugation improves the diagnosis of orthopaedics-related infections via real-time PCR amplification of the bacterial methicillin-resistance gene
por: Tsuru, Arisa, et al.
Publicado: (2015)

Association between Bone Mineral Density of Femoral Neck and Geriatric Nutritional Risk Index in Rheumatoid Arthritis Patients Treated with Biological Disease-Modifying Anti-Rheumatic Drugs
por: Tokumoto, Hiroto, et al.
Publicado: (2018)

Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation
por: Tanaka, M, et al.
Publicado: (2009)

Suppression of Matrix Metalloproteinase Production in Nasal Fibroblasts by Tranilast, an Antiallergic Agent, In Vitro
por: Shimizu, Toshiyuki, et al.
Publicado: (2005)

Pachydermodactyly Treated with Tranilast in a Young Girl
por: Higuchi, Chikahisa, et al.
Publicado: (2014)

TGF-β signaling induces SnoN to suppress BMP-induced hypertrophic maturation of chondrocytes
por: Maeda, Shingo, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_bmnd9g81skn2533barbpoho18n