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Silencing microRNA-27a inhibits proliferation and invasion of human osteosarcoma cells through the SFRP1-dependent Wnt/β-catenin signaling pathway

Osteosarcoma is the most common malignant tumor of bone with a high potential for metastasis. Importantly, microRNA-27a (miR-27a) is involved in the progression of osteosarcoma. The present study aims to discuss the effects of miR-27a and its target gene secreted frizzled related protein 1 (SFRP1) o...

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Detalles Bibliográficos
Autores principales: Mu, Yu, Zhang, Lina, Chen, Xue, Chen, Si, Shi, Yuanyuan, Li, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549093/
https://www.ncbi.nlm.nih.gov/pubmed/31072914
http://dx.doi.org/10.1042/BSR20182366