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Role of the S1P pathway and inhibition by fingolimod in preventing hemorrhagic transformation after stroke

Hemorrhagic transformation (HT) is a complication of severe ischemic stroke after revascularization. Patients with low platelet counts do not receive reperfusion therapies due to high risk of HT. The immunomodulatory drug fingolimod attenuated HT after tissue plasminogen activator in a thromboemboli...

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Detalles Bibliográficos
Autores principales:	Salas-Perdomo, Angélica, Miró-Mur, Francesc, Gallizioli, Mattia, Brait, Vanessa H., Justicia, Carles, Meissner, Anja, Urra, Xabier, Chamorro, Angel, Planas, Anna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549179/ https://www.ncbi.nlm.nih.gov/pubmed/31165772 http://dx.doi.org/10.1038/s41598-019-44845-5

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