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Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population

BACKGROUND: Epigenetics underlying refractory epilepsy is poorly understood. DNA methylation may affect gene expression in epilepsy patients without affecting DNA sequences. Herein, we investigated the association between Carbamazepine-resistant (CBZ-resistant) epilepsy and EPHX1 methylation in a no...

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Detalles Bibliográficos
Autores principales: Lv, Yudan, Zheng, Xiangyu, Shi, Mingchao, Wang, Zan, Cui, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549255/
https://www.ncbi.nlm.nih.gov/pubmed/31164100
http://dx.doi.org/10.1186/s12883-019-1308-4