Cargando…

Transfer Free Energies of Test Proteins Into Crowded Protein Solutions Have Simple Dependence on Crowder Concentration

The effects of macromolecular crowding on the thermodynamic properties of test proteins are determined by the latter's transfer free energies from a dilute solution to a crowded solution. The transfer free energies in turn are determined by effective protein-crowder interactions. When these int...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguemaha, Valery, Qin, Sanbo, Zhou, Huan-Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549383/ https://www.ncbi.nlm.nih.gov/pubmed/31192219 http://dx.doi.org/10.3389/fmolb.2019.00039

Ejemplares similares

Size of the protein-protein energy funnel in crowded environment
por: Jenkins, Nathan W., et al.
Publicado: (2022)

Crowding Effects on the Structure and Dynamics of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1
por: Bonucci, Alessio, et al.
Publicado: (2021)

Carbohydrate-Based Macromolecular Crowding-Induced Stabilization of Proteins: Towards Understanding the Significance of the Size of the Crowder
por: Shahid, Sumra, et al.
Publicado: (2019)

Modeling Crowded Environment in Molecular Simulations
por: Ostrowska, Natalia, et al.
Publicado: (2019)

Competitive Interactions of Ligands and Macromolecular Crowders with Maltose Binding Protein
por: Miklos, Andrew C., et al.
Publicado: (2013)

Allosterically coupled conformational dynamics in solution prepare the sterol transfer protein StarD4 to release its cargo upon interaction with target membranes
por: Xie, Hengyi, et al.
Publicado: (2023)

Revitalizing an important field in biophysics: The new frontiers of molecular crowding
por: Cammarata, Marco, et al.
Publicado: (2023)

Effects of Macromolecular Crowding on Protein Conformational Changes
por: Dong, Hao, et al.
Publicado: (2010)

Non-specific Interactions Between Macromolecular Solutes in Concentrated Solution: Physico-Chemical Manifestations and Biochemical Consequences
por: Hoppe, Travis, et al.
Publicado: (2019)

Structural Refolding and Thermal Stability of Myoglobin in the Presence of Mixture of Crowders: Importance of Various Interactions for Protein Stabilization in Crowded Conditions
por: Parray, Zahoor Ahmad, et al.
Publicado: (2021)

RASPD+: Fast Protein-Ligand Binding Free Energy Prediction Using Simplified Physicochemical Features
por: Holderbach, Stefan, et al.
Publicado: (2020)

Preferential Regulation of Transient Protein–Protein Interaction by the Macromolecular Crowders
por: Gong, Zhou, et al.
Publicado: (2022)

Opportunities and Challenges of Backbone, Sidechain, and RDC Experiments to Study Membrane Protein Dynamics in a Detergent-Free Lipid Environment Using Solution State NMR
por: Bibow, Stefan
Publicado: (2019)

Actin Bundle Nanomechanics and Organization Are Modulated by Macromolecular Crowding and Electrostatic Interactions
por: Castaneda, Nicholas, et al.
Publicado: (2021)

A Simple PB/LIE Free Energy Function Accurately Predicts the Peptide Binding Specificity of the Tiam1 PDZ Domain
por: Panel, Nicolas, et al.
Publicado: (2017)

Conjugative DNA Transfer Is Enhanced by Plasmid R1 Partitioning Proteins
por: Gruber, Christian J., et al.
Publicado: (2016)

DNA-Binding Proteins Regulating pIP501 Transfer and Replication
por: Grohmann, Elisabeth, et al.
Publicado: (2016)

Chemical shift transfer: an effective strategy for protein NMR assignment with ARTINA
por: Wetton, Henry, et al.
Publicado: (2023)

Editorial: Modulating Prokaryotic Lifestyle by DNA-Binding Proteins: Learning from (Apparently) Simple Systems
por: Venkova, Tatiana, et al.
Publicado: (2017)

Assessment of a Single Decoupling Alchemical Approach for the Calculation of the Absolute Binding Free Energies of Protein-Peptide Complexes
por: Kilburg, Denise, et al.
Publicado: (2018)

Phosphorylation and Alternative Translation on Wheat Germ Cell-Free Protein Synthesis of the DHBV Large Envelope Protein
por: David, Guillaume, et al.
Publicado: (2019)

AlphaFold Models of Small Proteins Rival the Accuracy of Solution NMR Structures
por: Tejero, Roberto, et al.
Publicado: (2022)

Crowding Induces Entropically-Driven Changes to DNA Dynamics That Depend on Crowder Structure and Ionic Conditions
por: Mardoum, Warren M., et al.
Publicado: (2018)

MicroRNAs in the Regulation of Solute Carrier Proteins Behind Xenobiotic and Nutrient Transport in Cells
por: Yi, Colleen, et al.
Publicado: (2022)

The Hypervariable Loops of Free TCRs Sample Multiple Distinct Metastable Conformations in Solution
por: Crooks, James E., et al.
Publicado: (2018)

Size-Dependent Interplay of Volume Exclusion Versus Soft Interactions: Cytochrome c in Macromolecular Crowded Environment
por: Parray, Zahoor Ahmad, et al.
Publicado: (2022)

Organization of the bacterial nucleoid by DNA-bridging proteins and globular crowders
por: Joyeux, Marc
Publicado: (2023)

Known Evolutionary Paths Are Accessible to Engineered ß-Lactamases Having Altered Protein Motions at the Timescale of Catalytic Turnover
por: Alejaldre, Lorea, et al.
Publicado: (2020)

Cell-Free Expression to Probe Co-Translational Insertion of an Alpha Helical Membrane Protein
por: Blackholly, Laura R., et al.
Publicado: (2022)

Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation
por: Wang, Shishan, et al.
Publicado: (2019)

Easy Synthesis of Complex Biomolecular Assemblies: Wheat Germ Cell-Free Protein Expression in Structural Biology
por: Fogeron, Marie-Laure, et al.
Publicado: (2021)

Energy Bilocalization Effect and the Emergence of Molecular Functions in Proteins
por: Chalopin, Yann, et al.
Publicado: (2021)

Small Things Matter: The 11.6-kDa TraB Protein is Crucial for Antibiotic Resistance Transfer Among Enterococci
por: Berger, Tamara M.I., et al.
Publicado: (2022)

Engagement of intrinsic disordered proteins in protein–protein interaction
por: Roterman, Irena, et al.
Publicado: (2023)

Biologically relevant small variations of intra-cellular pH can have significant effect on stability of protein–DNA complexes, including the nucleosome
por: Onufriev, Alexey V.
Publicado: (2023)

Diffusion of small molecule drugs is affected by surface interactions and crowder proteins
por: Dey, Debabrata, et al.
Publicado: (2022)

Prediction of protein-protein interaction sites in intrinsically disordered proteins
por: Chen, Ranran, et al.
Publicado: (2022)

Glycans of SARS-CoV-2 Spike Protein in Virus Infection and Antibody Production
por: Zhao, Xiaohui, et al.
Publicado: (2021)

A Review of Methodologies for the Detection, Quantitation, and Localization of Free Cysteine in Recombinant Proteins: A Focus on Therapeutic Monoclonal Antibodies
por: Metcalfe, Clive
Publicado: (2022)

Interactions Under Crowding Milieu: Chemical-Induced Denaturation of Myoglobin is Determined by the Extent of Heme Dissociation on Interaction with Crowders
por: Nasreen, Khalida, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k5sugue2rqeh4u4vv39uhq6hne