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Deferoxamine-induced high expression of TfR1 and DMT1 enhanced iron uptake in triple-negative breast cancer cells by activating IL-6/PI3K/AKT pathway
Background: Deferoxamine (DFO) is a commonly used iron chelator, which can reduce the iron levels in cells. DFO is normally used to treat iron-overload disease, including some types of cancer. However, our previous studies revealed that DFO treatment significantly increased the iron concentrations i...
Autores principales: | Chen, Chunli, Liu, Ping, Duan, Xiaoyue, Cheng, Man, Xu, Lisa X |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549404/ https://www.ncbi.nlm.nih.gov/pubmed/31213851 http://dx.doi.org/10.2147/OTT.S193507 |
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