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Systems Chemical Genetics-Based Drug Discovery: Prioritizing Agents Targeting Multiple/Reliable Disease-Associated Genes as Drug Candidates
Genetic disease genes are considered a promising source of drug targets. Most diseases are caused by more than one pathogenic factor; thus, it is reasonable to consider that chemical agents targeting multiple disease genes are more likely to have desired activities. This is supported by a comprehens...
Autores principales: | Quan, Yuan, Luo, Zhi-Hui, Yang, Qing-Yong, Li, Jiang, Zhu, Qiang, Liu, Ye-Mao, Lv, Bo-Min, Cui, Ze-Jia, Qin, Xuan, Xu, Yan-Hua, Zhu, Li-Da, Zhang, Hong-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549477/ https://www.ncbi.nlm.nih.gov/pubmed/31191604 http://dx.doi.org/10.3389/fgene.2019.00474 |
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