Cargando…

Elucidating a false-negative MYC break-apart fluorescence in situ hybridization probe study by next-generation sequencing in a patient with high-grade B-cell lymphoma with IGH/MYC and IGH/BCL2 rearrangements

The identification of MYC rearrangements in several mature B-cell neoplasms is critical for diagnostic and prognostic purposes. Commercially available fluorescence in situ hybridization (FISH) probe sets, including IGH/MYC dual-color dual-fusion (D-FISH) and MYC break-apart probes (BAPs), serve as t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peterson, Jess F., Pitel, Beth A., Smoley, Stephanie A., Vasmatzis, George, Smadbeck, James B., Greipp, Patricia T., Ketterling, Rhett P., Macon, William R., Baughn, Linda B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549546/ https://www.ncbi.nlm.nih.gov/pubmed/31160360 http://dx.doi.org/10.1101/mcs.a004077

Ejemplares similares

Plasmablastic lymphoma with MYC::IGH fusion and BCL2 rearrangement
por: Barouqa, Mohammad, et al.
Publicado: (2022)

Double-Hit Primary Plasma Cell Leukemia with IGH/MYC and IGH/CCND1 Translocations
por: Yasumi, Masato, et al.
Publicado: (2020)

Characterization of TCF3 rearrangements in pediatric B-lymphoblastic leukemia/lymphoma by mate-pair sequencing (MPseq) identifies complex genomic rearrangements and a novel TCF3/TEF gene fusion
por: Rowsey, Ross A., et al.
Publicado: (2019)

Genetic features of precursor B‐cell phenotype Burkitt leukemia with IGH‐ MYC rearrangement
por: Yoshida, Masanori, et al.
Publicado: (2021)

Long-range Oncogenic Activation of IgH/c-myc Translocations by the IgH 3’ Regulatory Region
por: Gostissa, Monica, et al.
Publicado: (2009)

Enhancer RNA AL928768.3 from the IGH Locus Regulates MYC Expression and Controls the Proliferation and Chemoresistance of Burkitt Lymphoma Cells with IGH/MYC Translocation
por: Stasevich, Ekaterina Mikhailovna, et al.
Publicado: (2022)

Inferior survival in high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements is not associated with MYC/IG gene rearrangements
por: McPhail, Ellen D., et al.
Publicado: (2018)

PB1913: IGH 3’RR RECOMBINATION UNCOVERS A NON-GC IMPRINT AND C-MYC-DEPENDENT IGH REARRANGEMENT ACTIVITY IN UNMUTATED CHRONIC LYMPHOCYTIC LEUKEMIA
por: Jamal, Israa Al, et al.
Publicado: (2023)

Myc Dynamically and Preferentially Relocates to a Transcription Factory Occupied by Igh
por: Osborne, Cameron S, et al.
Publicado: (2007)

Nucleolar tethering mediates pairing between the IgH and Myc loci
por: Strongin, Daniel E, et al.
Publicado: (2014)

MYC break-apart FISH probe set reveals frequent unbalanced patterns of uncertain significance when evaluating aggressive B-cell lymphoma
por: Gagnon, Marie-France, et al.
Publicado: (2021)

Submicroscopic Deletions of Immunoglobulin Heavy Chain Gene (IGH) in Precursor B Lymphoblastic Leukemia with IGH Rearrangements
por: Huh, Jungwon, et al.
Publicado: (2015)

The Prognostic Role of MYC Structural Variants Identified by NGS and FISH in Multiple Myeloma
por: Sharma, Neeraj, et al.
Publicado: (2021)

The IgH 3′ regulatory region influences lymphomagenesis in Igλ-Myc mice
por: Saad, Faten, et al.
Publicado: (2015)

The IgH 3’ regulatory region and c-myc-induced B-cell lymphomagenesis
por: Ghazzaui, Nour, et al.
Publicado: (2016)

A role for AID in chromosome translocations between c-myc and the IgH variable region
por: Dorsett, Yair, et al.
Publicado: (2007)

A role for AID in chromosome translocations between c-myc and the IgH variable region
por: Dorsett, Yair, et al.
Publicado: (2007)

Generation and characteristics of a novel “double-hit” high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies
por: Kikuchi, Hiroaki, et al.
Publicado: (2018)

“Double hit” B-lymphoblastic lymphoma with concurrent IGH/BCL2 and 8q24/MYC translocations: a case report
por: He, Lu, et al.
Publicado: (2021)

Improvement of diagnosis in children with Burkitt lymphoma in Kenya: feasibility study for the implementation of fluorescence in situ hybridisation testing for MYC and the MYC/IGH translocation
por: Vance, Gail H, et al.
Publicado: (2023)

Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors
por: Li, Weiping, et al.
Publicado: (2019)

Detection of a cryptic NUP214/ABL1 gene fusion by mate-pair sequencing (MPseq) in a newly diagnosed case of pediatric T-lymphoblastic leukemia
por: Peterson, Jess F., et al.
Publicado: (2019)

CD5-negative Blastoid Variant Mantle Cell Lymphoma with Complex CCND1/IGH and MYC Aberrations
por: Seok, Yoonmi, et al.
Publicado: (2012)

Mouse Models of c-myc Deregulation Driven by IgH Locus Enhancers as Models of B-Cell Lymphomagenesis
por: Ferrad, Melissa, et al.
Publicado: (2020)

Increased complexity of t(11;14) rearrangements in plasma cell neoplasms compared with mantle cell lymphoma
por: Dalland, Joanna C., et al.
Publicado: (2021)

B-ALL With t(5;14)(q31;q32); IGH-IL3 Rearrangement and Eosinophilia: A Comprehensive Analysis of a Peculiar IGH-Rearranged B-ALL
por: Fournier, Benjamin, et al.
Publicado: (2019)

Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL
por: Brazdilova, K, et al.
Publicado: (2018)

IgH gene rearrangements as plasma biomarkers in Non-Hodgkin's Lymphoma patients
por: He, Jian, et al.
Publicado: (2011)

3’Igh enhancers hs3b/hs4 are dispensable for Myc deregulation in mouse plasmacytomas with T(12;15) translocations
por: Kovalchuk, Alexander L., et al.
Publicado: (2018)

Atypical rearrangement involving 3′-IGH@ and a breakpoint at least 400 Kb upstream of an intact MYC in a CLL patient with an apparently balanced t(8;14)(q24.1;q32) and negative MYC expression
por: Amarillo, Ina, et al.
Publicado: (2013)

Misregulation of the IgH Locus in Thymocytes
por: Kumari, Gita, et al.
Publicado: (2018)

Mate pair sequencing improves detection of genomic abnormalities in acute myeloid leukemia
por: Aypar, Umut, et al.
Publicado: (2018)

Inter- and intratumoral heterogeneity of BCL2 correlates with IgH expression and prognosis in follicular lymphoma
por: Barreca, A, et al.
Publicado: (2014)

Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci
por: Inlay, Matthew A., et al.
Publicado: (2006)

Novel rearrangements at the immunoglobulin D locus. Inversions and fusions add to IgH somatic diversity
Publicado: (1989)

Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing
por: Wu, Jinghua, et al.
Publicado: (2016)

Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia
por: Tian, Liqing, et al.
Publicado: (2019)

Contribution of the IGCR1 regulatory element and the 3′Igh CTCF-binding elements to regulation of Igh V(D)J recombination
por: Liang, Zhuoyi, et al.
Publicado: (2023)

A double‐hit High‐grade B‐cell lymphoma with three‐way translocation t(3;8;14)(q27;q24;q32) involving BCL6, MYC, and IGH
por: De Paoli, Elena, et al.
Publicado: (2018)

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination
por: Robert, Isabelle, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_jo8oapsll0hh4lg14cid2768u9