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Urothelial carcinoma with an NRF1-BRAF rearrangement and response to targeted therapy

Although BRAF mutations are commonly identified in many solid tumors and the response of BRAF p.V600E-positive tumors to targeted therapy is well documented, BRAF rearrangements are less frequent and are predominantly found in low-grade glioma, melanoma, lung, colorectal, and thyroid carcinoma. Prec...

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Detalles Bibliográficos
Autores principales: Isaacson, Alexandra L., Guseva, Natalya V., Bossler, Aaron D., Ma, Deqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549557/
https://www.ncbi.nlm.nih.gov/pubmed/31010895
http://dx.doi.org/10.1101/mcs.a003848

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