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Release of active peptidylarginine deiminase into the circulation during acute inflammation induced by coronary artery bypass surgery

Purpose: Peptidylarginine deiminase (PAD) catalyzes citrullination, a post-translational modification that can alter structure, function and antigenicity of proteins. Citrullination in the lungs due to smoking is believed to initiate an anti-citrulline immune response in rheumatoid arthritis. Citrul...

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Detalles Bibliográficos
Autores principales: Vejlstrup, Anne, Møller, Ann Merete, Nielsen, Claus Henrik, Damgaard, Dres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549760/
https://www.ncbi.nlm.nih.gov/pubmed/31213874
http://dx.doi.org/10.2147/JIR.S198611

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