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C-terminal truncated HBx reduces doxorubicin cytotoxicity via ABCB1 upregulation in Huh-7 hepatocellular carcinoma cells

Hepatitis B virus (HBV) encoding the HBV x protein (HBx) is a known causative agent of hepatocellular carcinoma (HCC). Its pathogenic activities in HCC include interference with several signaling pathways associated with cell proliferation and apoptosis. Mutant C-terminal-truncated HBx isoforms are...

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Detalles Bibliográficos
Autores principales: Jegal, Myeong-Eun, Jung, Seung-Youn, Han, Yu-Seon, Kim, Yung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549916/
https://www.ncbi.nlm.nih.gov/pubmed/30982500
http://dx.doi.org/10.5483/BMBRep.2019.52.5.312

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