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Ion channel gating in cardiac ryanodine receptors from the arrhythmic RyR2-P2328S mouse

Mutations in the cardiac ryanodine receptor Ca(2+) release channel (RyR2) can cause deadly ventricular arrhythmias and atrial fibrillation (AF). The RyR2-P2328S mutation produces catecholaminergic polymorphic ventricular tachycardia (CPVT) and AF in hearts from homozygous RyR2(P2328S/P2328S) (denote...

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Detalles Bibliográficos
Autores principales:	Salvage, Samantha C., Gallant, Esther M., Beard, Nicole A., Ahmad, Shiraz, Valli, Haseeb, Fraser, James A., Huang, Christopher L.-H., Dulhunty, Angela F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550012/ https://www.ncbi.nlm.nih.gov/pubmed/31028179 http://dx.doi.org/10.1242/jcs.229039

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