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Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice

One diagnostic feature of craniosynostosis syndromes is mandibular dysgenesis. Using three mouse models of Apert, Crouzon and Pfeiffer craniosynostosis syndromes, we investigated how embryonic development of the mandible is affected by fibroblast growth factor receptor 2 (Fgfr2) mutations. Quantitat...

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Detalles Bibliográficos
Autores principales:	Motch Perrine, Susan M., Wu, Meng, Stephens, Nicholas B., Kriti, Divya, van Bakel, Harm, Jabs, Ethylin Wang, Richtsmeier, Joan T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550049/ https://www.ncbi.nlm.nih.gov/pubmed/31064775 http://dx.doi.org/10.1242/dmm.038513

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