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Optical sensor revealed abnormal nuclease spatial activity on cancer cell membrane
Nucleases are important enzymes that cleave nucleic acids and play critical roles in DNA repair, immune defense and potentially in cancer invasion. However, their spatial dynamics at subcellular level is much less studied. Here, we developed a surface‐tethered nuclease sensor (SNS) which directly co...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
WILEY‐VCH Verlag GmbH & Co. KGaA
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550314/ https://www.ncbi.nlm.nih.gov/pubmed/30488667 http://dx.doi.org/10.1002/jbio.201800351 |