Cargando…

NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors

Netrin-G ligand-3 (NGL-3) is a postsynaptic adhesion molecule known to directly interact with the excitatory postsynaptic scaffolding protein postsynaptic density-95 (PSD-95) and trans-synaptically with leukocyte common antigen-related (LAR) family receptor tyrosine phosphatases to regulate presynap...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hyejin, Shin, Wangyong, Kim, Kyungdeok, Lee, Suho, Lee, Eun-Jae, Kim, Jihye, Kweon, Hanseul, Lee, Eunee, Park, Haram, Kang, Muwon, Yang, Esther, Kim, Hyun, Kim, Eunjoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550391/ https://www.ncbi.nlm.nih.gov/pubmed/31166939 http://dx.doi.org/10.1371/journal.pbio.2005326

Ejemplares similares

NGL-1/LRRC4C-Mutant Mice Display Hyperactivity and Anxiolytic-Like Behavior Associated With Widespread Suppression of Neuronal Activity
por: Choi, Yeonsoo, et al.
Publicado: (2019)

Shank2 Deletion in Parvalbumin Neurons Leads to Moderate Hyperactivity, Enhanced Self-Grooming and Suppressed Seizure Susceptibility in Mice
por: Lee, Seungjoon, et al.
Publicado: (2018)

NGL-1/LRRC4C Deletion Moderately Suppresses Hippocampal Excitatory Synapse Development and Function in an Input-Independent Manner
por: Choi, Yeonsoo, et al.
Publicado: (2019)

Presynaptic PTPσ regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanisms
por: Kim, Kyungdeok, et al.
Publicado: (2020)

Scn2a Haploinsufficiency in Mice Suppresses Hippocampal Neuronal Excitability, Excitatory Synaptic Drive, and Long-Term Potentiation, and Spatial Learning and Memory
por: Shin, Wangyong, et al.
Publicado: (2019)

Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/γ-secretase
por: Lee, Hyejin, et al.
Publicado: (2014)

Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice
por: Shin, Wangyong, et al.
Publicado: (2020)

Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation
por: Lee, Eun-Jae, et al.
Publicado: (2015)

SALM4 negatively regulates NMDA receptor function and fear memory consolidation
por: Lie, Eunkyung, et al.
Publicado: (2021)

Splice‐dependent trans‐synaptic PTPδ–IL1RAPL1 interaction regulates synapse formation and non‐REM sleep
por: Park, Haram, et al.
Publicado: (2020)

Age-differential sexual dimorphism in CHD8-S62X-mutant mouse behaviors
por: Lee, Soo Yeon, et al.
Publicado: (2022)

Age-differential sexual dimorphisms in CHD8-S62X-mutant mouse synapses and transcriptomes
por: Lee, Soo Yeon, et al.
Publicado: (2023)

Gene Dosage- and Age-Dependent Differential Transcriptomic Changes in the Prefrontal Cortex of Shank2-Mutant Mice
por: Lee, Seungjoon, et al.
Publicado: (2021)

Different expression of GSK3β and pS9GSK3β depending on phenotype of cervical cancer: possible association of GSK3β with squamous cell carcinoma and pS9GSK3β with adenocarcinoma
por: Ahn, Kwanghee, et al.
Publicado: (2019)

Shank3 Exons 14–16 Deletion in Glutamatergic Neurons Leads to Social and Repetitive Behavioral Deficits Associated With Increased Cortical Layer 2/3 Neuronal Excitability
por: Yoo, Taesun, et al.
Publicado: (2019)

Suppressed prefrontal neuronal firing variability and impaired social representation in IRSp53-mutant mice
por: Kim, Woohyun, et al.
Publicado: (2022)

Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons
por: Kim, Sun-Gyun, et al.
Publicado: (2021)

Author Correction: Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons
por: Kim, Sun-Gyun, et al.
Publicado: (2022)

GABA Neuronal Deletion of Shank3 Exons 14–16 in Mice Suppresses Striatal Excitatory Synaptic Input and Induces Social and Locomotor Abnormalities
por: Yoo, Taesun, et al.
Publicado: (2018)

Synapse maintenance and restoration in the retina by NGL2
por: Soto, Florentina, et al.
Publicado: (2018)

Neuroprotective Effects of Salicin in a Gerbil Model of Transient Forebrain Ischemia by Attenuating Oxidative Stress and Activating PI3K/Akt/GSK3β Pathway
por: Park, Joon-Ha, et al.
Publicado: (2021)

IRSp53 Deletion in Glutamatergic and GABAergic Neurons and in Male and Female Mice Leads to Distinct Electrophysiological and Behavioral Phenotypes
por: Kim, Yangsik, et al.
Publicado: (2020)

Corrigendum: IRSp53 Deletion in Glutamatergic and GABAergic Neurons and in Male and Female Mice Leads to Distinct Electrophysiological and Behavioral Phenotypes
por: Kim, Yangsik, et al.
Publicado: (2021)

NGL Viewer: a web application for molecular visualization
por: Rose, Alexander S., et al.
Publicado: (2015)

Assessment of Empirical Troposphere Model GPT3 Based on NGL’s Global Troposphere Products
por: Ding, Junsheng, et al.
Publicado: (2020)

Splicing-Dependent Trans-synaptic SALM3–LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion
por: Li, Yan, et al.
Publicado: (2015)

GSK-3β activation is required for ZIP-induced disruption of learned fear
por: Song, Sukwoon, et al.
Publicado: (2020)

Inhibition of PI3K/Akt signaling suppresses epithelial-to-mesenchymal transition in hepatocellular carcinoma through the Snail/GSK-3/beta-catenin pathway
por: Lee, Seulki, et al.
Publicado: (2020)

Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice
por: Lee, Eunee, et al.
Publicado: (2021)

Function and mechanism of tumor suppressor gene LRRC4/NGL-2
por: Li, Peiyao, et al.
Publicado: (2014)

TRIB2 Stimulates Cancer Stem-Like Properties through Activating the AKT-GSK3β-β-Catenin Signaling Axis
por: Kim, Dae Kyoung, et al.
Publicado: (2021)

IRSp53 promotes postsynaptic density formation and actin filament bundling
por: Feng, Zhe, et al.
Publicado: (2022)

Inhibition of AKT/GSK3β/CREB Pathway Improves the Responsiveness to AMPA Receptor Antagonists by Regulating GRIA1 Surface Expression in Chronic Epilepsy Rats
por: Kim, Ji-Eun, et al.
Publicado: (2021)

Structural basis for cell surface patterning through NetrinG–NGL interactions
por: Seiradake, Elena, et al.
Publicado: (2011)

Mice lacking the synaptic adhesion molecule Neph2/Kirrel3 display moderate hyperactivity and defective novel object preference
por: Choi, Su-Yeon, et al.
Publicado: (2015)

A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice
por: Yook, Chaehyun, et al.
Publicado: (2019)

GSK3B induces autophagy by phosphorylating ULK1
por: Ryu, Hye Young, et al.
Publicado: (2021)

AKT/GSK3 signaling pathway and schizophrenia
por: Emamian, Effat S.
Publicado: (2012)

AKT/GSK3β Signaling in Glioblastoma
por: Majewska, Ewelina, et al.
Publicado: (2016)

Saccharomyces cerevisiae Ngl3p is an active 3′–5′ exonuclease with a specificity towards poly-A RNA reminiscent of cellular deadenylases
por: Feddersen, Ane, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_8tp1s79pgk4u6jq9qk5t0ic04l