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Association between MICA polymorphisms, s-MICA levels, and pancreatic cancer risk in a population-based case-control study

BACKGROUND: Pancreatic tumor cells may avoid immune surveillance by releasing the transmembrane major histocompatibility complex class I chain-related A (MICA) protein in soluble form (s-MICA). We hypothesized that the presence of the A5.1 polymorphism in the MICA gene, which encodes a truncated MIC...

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Detalles Bibliográficos
Autores principales: Onyeaghala, Guillaume, Lane, John, Pankratz, Nathan, Nelson, Heather H., Thyagarajan, Bharat, Walcheck, Bruce, Anderson, Kristin E., Prizment, Anna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550421/
https://www.ncbi.nlm.nih.gov/pubmed/31166958
http://dx.doi.org/10.1371/journal.pone.0217868