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Direct Amination of Cobaltocenium Hexafluoridophosphate via Vicarious Nucleophilic Substitution
[Image: see text] In this communication we report a convenient, as short as possible synthesis of aminocobaltocenium hexafluoridophosphate, a very useful compound for further functionalization in cobaltocenium chemistry. Via vicarious nucleophilic substitution of hydrogen of cobaltocenium hexafluori...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550438/ https://www.ncbi.nlm.nih.gov/pubmed/31178615 http://dx.doi.org/10.1021/acs.organomet.9b00205 |
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author | Jochriem, Markus Bosch, Dominik Kopacka, Holger Bildstein, Benno |
author_facet | Jochriem, Markus Bosch, Dominik Kopacka, Holger Bildstein, Benno |
author_sort | Jochriem, Markus |
collection | PubMed |
description | [Image: see text] In this communication we report a convenient, as short as possible synthesis of aminocobaltocenium hexafluoridophosphate, a very useful compound for further functionalization in cobaltocenium chemistry. Via vicarious nucleophilic substitution of hydrogen of cobaltocenium hexafluoridophosphate with 1,1,1-trimethylhydrazinium iodide as nucleophile bearing its own leaving group, a one-step amination of cobaltocenium in 50% isolated yield is possible, a major improvement over the standard multistep procedure involving common Curtius rearrangement chemistry. |
format | Online Article Text |
id | pubmed-6550438 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-65504382019-06-07 Direct Amination of Cobaltocenium Hexafluoridophosphate via Vicarious Nucleophilic Substitution Jochriem, Markus Bosch, Dominik Kopacka, Holger Bildstein, Benno Organometallics [Image: see text] In this communication we report a convenient, as short as possible synthesis of aminocobaltocenium hexafluoridophosphate, a very useful compound for further functionalization in cobaltocenium chemistry. Via vicarious nucleophilic substitution of hydrogen of cobaltocenium hexafluoridophosphate with 1,1,1-trimethylhydrazinium iodide as nucleophile bearing its own leaving group, a one-step amination of cobaltocenium in 50% isolated yield is possible, a major improvement over the standard multistep procedure involving common Curtius rearrangement chemistry. American Chemical Society 2019-05-17 2019-05-28 /pmc/articles/PMC6550438/ /pubmed/31178615 http://dx.doi.org/10.1021/acs.organomet.9b00205 Text en Copyright © 2019 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited. |
spellingShingle | Jochriem, Markus Bosch, Dominik Kopacka, Holger Bildstein, Benno Direct Amination of Cobaltocenium Hexafluoridophosphate via Vicarious Nucleophilic Substitution |
title | Direct Amination of Cobaltocenium Hexafluoridophosphate
via Vicarious Nucleophilic Substitution |
title_full | Direct Amination of Cobaltocenium Hexafluoridophosphate
via Vicarious Nucleophilic Substitution |
title_fullStr | Direct Amination of Cobaltocenium Hexafluoridophosphate
via Vicarious Nucleophilic Substitution |
title_full_unstemmed | Direct Amination of Cobaltocenium Hexafluoridophosphate
via Vicarious Nucleophilic Substitution |
title_short | Direct Amination of Cobaltocenium Hexafluoridophosphate
via Vicarious Nucleophilic Substitution |
title_sort | direct amination of cobaltocenium hexafluoridophosphate
via vicarious nucleophilic substitution |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550438/ https://www.ncbi.nlm.nih.gov/pubmed/31178615 http://dx.doi.org/10.1021/acs.organomet.9b00205 |
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