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Uncoupling the Threading and Unfoldase Actions of Plasmodium HSP101 Reveals Differences in Export between Soluble and Insoluble Proteins

Plasmodium parasites must export proteins into their erythrocytic host to survive. Exported proteins must cross the parasite plasma membrane (PPM) and the parasitophorous vacuolar membrane (PVM) encasing the parasite to access the host cell. Crossing the PVM requires protein unfolding and passage th...

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Detalles Bibliográficos
Autores principales: Matthews, Kathryn M., Kalanon, Ming, de Koning-Ward, Tania F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550532/
https://www.ncbi.nlm.nih.gov/pubmed/31164473
http://dx.doi.org/10.1128/mBio.01106-19