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MON-367 A Case of Bilateral Adrenal Hemorrhage Initially Diagnosed as Bilateral Adrenal Adenomas in a Patient without Typical Risk Factors

Background: Adrenal insufficiency secondary to bilateral adrenal hemorrhage in adults is a rare but life-threatening occurrence. Rarer still are cases of bilateral adrenal hemorrhage in atraumatic patients not on anticoagulation and without bleeding or clotting disorders. Clinical Case: We report a...

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Autores principales: Villasante Fricke, Alexandra, Madala, Sravanthi, Correa, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550624/
http://dx.doi.org/10.1210/js.2019-MON-367
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author Villasante Fricke, Alexandra
Madala, Sravanthi
Correa, Ricardo
author_facet Villasante Fricke, Alexandra
Madala, Sravanthi
Correa, Ricardo
author_sort Villasante Fricke, Alexandra
collection PubMed
description Background: Adrenal insufficiency secondary to bilateral adrenal hemorrhage in adults is a rare but life-threatening occurrence. Rarer still are cases of bilateral adrenal hemorrhage in atraumatic patients not on anticoagulation and without bleeding or clotting disorders. Clinical Case: We report a case of a 78 year old woman found to have bilateral adrenal hemorrhage. Patient was taking aspirin 81mg daily but she was not on anticoagulant medication. She has no history of bleeding or clotting disorders. She denies recent trauma or surgery. Patient initially presented with recurrent syncope and hypotension and CT scan of the abdomen and pelvis revealed bilateral adrenal masses. Work-up of adrenal masses was negative for pheochromocytoma and Cushing’s syndrome. Magnetic resonance imaging of the abdomen was then performed which revealed bilateral adrenal hemorrhage. Patient subsequently underwent a cosyntropin stimulation test and this was consistent with adrenal insufficiency. Conclusions: Adrenal hemorrhage should be on the differential in the event of bilateral adrenal masses diagnosed on CT scan. In this case, MRI was diagnostic of adrenal hemorrhage while CT was not. This patient required both glucocorticoid and mineralocorticoid replacement. Patient recovered and did well after adrenal replacement was started.
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spelling pubmed-65506242019-06-13 MON-367 A Case of Bilateral Adrenal Hemorrhage Initially Diagnosed as Bilateral Adrenal Adenomas in a Patient without Typical Risk Factors Villasante Fricke, Alexandra Madala, Sravanthi Correa, Ricardo J Endocr Soc Adrenal Background: Adrenal insufficiency secondary to bilateral adrenal hemorrhage in adults is a rare but life-threatening occurrence. Rarer still are cases of bilateral adrenal hemorrhage in atraumatic patients not on anticoagulation and without bleeding or clotting disorders. Clinical Case: We report a case of a 78 year old woman found to have bilateral adrenal hemorrhage. Patient was taking aspirin 81mg daily but she was not on anticoagulant medication. She has no history of bleeding or clotting disorders. She denies recent trauma or surgery. Patient initially presented with recurrent syncope and hypotension and CT scan of the abdomen and pelvis revealed bilateral adrenal masses. Work-up of adrenal masses was negative for pheochromocytoma and Cushing’s syndrome. Magnetic resonance imaging of the abdomen was then performed which revealed bilateral adrenal hemorrhage. Patient subsequently underwent a cosyntropin stimulation test and this was consistent with adrenal insufficiency. Conclusions: Adrenal hemorrhage should be on the differential in the event of bilateral adrenal masses diagnosed on CT scan. In this case, MRI was diagnostic of adrenal hemorrhage while CT was not. This patient required both glucocorticoid and mineralocorticoid replacement. Patient recovered and did well after adrenal replacement was started. Endocrine Society 2019-04-30 /pmc/articles/PMC6550624/ http://dx.doi.org/10.1210/js.2019-MON-367 Text en Copyright © 2019 Endocrine Society https://creativecommons.org/licenses/by-nc-nd/4.0/ This article has been published under the terms of the Creative Commons Attribution Non-Commercial, No-Derivatives License (CC BY-NC-ND; https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Adrenal
Villasante Fricke, Alexandra
Madala, Sravanthi
Correa, Ricardo
MON-367 A Case of Bilateral Adrenal Hemorrhage Initially Diagnosed as Bilateral Adrenal Adenomas in a Patient without Typical Risk Factors
title MON-367 A Case of Bilateral Adrenal Hemorrhage Initially Diagnosed as Bilateral Adrenal Adenomas in a Patient without Typical Risk Factors
title_full MON-367 A Case of Bilateral Adrenal Hemorrhage Initially Diagnosed as Bilateral Adrenal Adenomas in a Patient without Typical Risk Factors
title_fullStr MON-367 A Case of Bilateral Adrenal Hemorrhage Initially Diagnosed as Bilateral Adrenal Adenomas in a Patient without Typical Risk Factors
title_full_unstemmed MON-367 A Case of Bilateral Adrenal Hemorrhage Initially Diagnosed as Bilateral Adrenal Adenomas in a Patient without Typical Risk Factors
title_short MON-367 A Case of Bilateral Adrenal Hemorrhage Initially Diagnosed as Bilateral Adrenal Adenomas in a Patient without Typical Risk Factors
title_sort mon-367 a case of bilateral adrenal hemorrhage initially diagnosed as bilateral adrenal adenomas in a patient without typical risk factors
topic Adrenal
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550624/
http://dx.doi.org/10.1210/js.2019-MON-367
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