MON-477 Octreotide and ONO-ST-468, a Novel and Potent Somatostatin Receptor Type-2 (SST2) Agonist, Suppress GH Hypersecretion in the Monkey

Purpose: The verification of efficacy of new drug candidates in primate models may address the translational gap between non-clinical and clinical studies and support the prediction of efficacy in humans. Given this, and to support the evaluation of novel SST2 agonists, a GHRH/arginine-induced GH hy...

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Detalles Bibliográficos
Autores principales: Tanaka, Hirotaka, Komagata, Tatsuya, Nishio, Takuya, Ishida, Akiharu, Okada, Hiroki, Katsumata, Seishi, Shinozaki, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550638/
http://dx.doi.org/10.1210/js.2019-MON-477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550638/
http://dx.doi.org/10.1210/js.2019-MON-477

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