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MON-357 Recurrent Adrenal Crises in a Cytochrome P450 Ultra-Rapid Metabolizer

Background The cytochrome P450s (CYPs) are a superfamily of oxidative enzymes of which the CYP3A subfamily is responsible for the metabolism of approximately 50% of all drugs. This includes exogenous and endogenous steroids. Over 20 polymorphisms of CYP3A4 have been described with three metabolic ph...

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Detalles Bibliográficos
Autores principales: Meyreles Chaljub, Gustavo, Torres Potter, Losty, Troya, Pedro, Candelario-Cosme, Madeline, Weare-Regales, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550675/
http://dx.doi.org/10.1210/js.2019-MON-357

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