MON-222 Blocking GABAB Receptors (GABABR) from Birth to Weaning in Mice Induces Profound Changes in the Gonadotropic Axis

We have previously shown that the administration of a GABAB antagonist (CGP55845) to neonatal BALB/C mice from postnatal day (PND) 2-6 significantly decreased arcuate nucleus (ARC) kisspeptin (Kiss1) expression in both sexes. Furthermore, this neonatal CGP55845 treatment delayed puberty onset in fem...

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Detalles Bibliográficos
Autores principales: Bizzozzero Hiriart, Marianne, Di Giorgio, Noelia, Libertun, Carlos, Lux-Lantos, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Reproductive Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550678/
http://dx.doi.org/10.1210/js.2019-MON-222

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