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MON-482 Sex-Dependent Biphasic Response by Somatotropes to Fasting and Loss of Leptin Signaling
Fasting results in a well-established rise in serum growth hormone (GH) in mice and humans. In mice, this coincides with increases in Gh and growth hormone releasing hormone receptor (Ghrhr) mRNA, as well as serum ghrelin. However, fasting also results in a dramatic decline in serum leptin and we ha...
Autores principales: | Miles, Tiffany, Silva Moreira, Ana Rita, Allensworth, Melody, Odle, Angela, Haney, Anessa, MacNicol, Angus, Childs, Gwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550701/ http://dx.doi.org/10.1210/js.2019-MON-482 |
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