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MON-480 Reduced Respiration Observed In Isolated Liver Mitochondria Of Long-lived GHR-/- Mice At Early Ages

The relationship between growth hormone (GH) and cellular metabolism is not completely understood, and its effect on mitochondria could play a crucial role in the aging process as implicated by the ‘Mitochondrial Free Radical Theory of Aging’(1). Previous studies on GHR-/- mice with extended lifespa...

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Detalles Bibliográficos
Autores principales: Funk, Kevin, Qian, Yanrong, List, Edward, Berryman, Darlene, Kopchick, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550804/
http://dx.doi.org/10.1210/js.2019-MON-480