Cargando…
MON-187 The E23K Missense Variant of the Gene Encoding the Pancreatic Beta-Cell KATP Channel Subunit Kir6.2 (KCNJ11) Associates with Diabetic Retinopathy and Hyperglycemia Control in Type 2 Diabetes Patients
BACKGROUND. The ATP-sensitive K (K(ATP)) channel regulates insulin sensitivity, by linking insulin secretion to changes in blood glucose levels. HYPOTHESIS. Kir6.2 is a specific point mutation in KCNJ11 gene, which encodes the pore-forming subunit of the pancreatic K(ATP) channel, and was reportedly...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550821/ http://dx.doi.org/10.1210/js.2019-MON-187 |