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MON-LB020 Compound H Causes a Sustained Reduction in Food Intake and Body Weight in Obese Cynomolgus

Obesity is associated with increased risk of diabetes and cardiovascular disease. Evidence is accumulating that significant WL (>10%) may reduce this risk. GDF15 is a secreted circulating polypeptide associated with energy balance. The receptor for GDF15, Gfral, is expressed in the area postrema...

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Detalles Bibliográficos
Autores principales:	Hinke, Simon, Zheng, Songmao, Wang, Yuanping, Brian, Geist, Fei, Chen, Peggy, Wong, Katharine, D’Aquino, Stojanvic-Susulic, Vedrana, Rangwala, Shamina, Nawrocki, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Adipose Tissue, Appetite, and Obesity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550856/ http://dx.doi.org/10.1210/js.2019-MON-LB020

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