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MON-LB019 Setmelanotide (RM-493) Reduces Food Intake and Rapidly Induces Weight Loss in a Mouse Model of Alström Syndrome
Introduction Alström syndrome (AS) is an autosomal recessive ciliopathy caused by mutations in ALMS1, which encodes a protein that localizes to centrosomes and basal bodies of primary cilia. Early emergence of obesity in patients with AS suggests a key r...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550858/ http://dx.doi.org/10.1210/js.2019-MON-LB019 |