Cargando…

EF-G–induced ribosome sliding along the noncoding mRNA

Translational bypassing is a recoding event during which ribosomes slide over a noncoding region of the messenger RNA (mRNA) to synthesize one protein from two discontinuous reading frames. Structures in the mRNA orchestrate forward movement of the ribosome, but what causes ribosomes to start slidin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klimova, M., Senyushkina, T., Samatova, E., Peng, B. Z., Pearson, M., Peske, F., Rodnina, M. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551183/ https://www.ncbi.nlm.nih.gov/pubmed/31183409 http://dx.doi.org/10.1126/sciadv.aaw9049

Ejemplares similares

Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome
por: Adio, Sarah, et al.
Publicado: (2015)

Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs
por: Korniy, Natalia, et al.
Publicado: (2019)

Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting
por: Caliskan, Neva, et al.
Publicado: (2015)

Translational recoding: canonical translation mechanisms reinterpreted
por: Rodnina, Marina V, et al.
Publicado: (2020)

Dynamics of ribosomes and release factors during translation termination in E. coli
por: Adio, Sarah, et al.
Publicado: (2018)

Ribosome rearrangements at the onset of translational bypassing
por: Agirrezabala, Xabier, et al.
Publicado: (2017)

Effect of Fusidic Acid on the Kinetics of Molecular Motions During EF-G-Induced Translocation on the Ribosome
por: Belardinelli, Riccardo, et al.
Publicado: (2017)

Cotranslational Folding of Proteins on the Ribosome
por: Liutkute, Marija, et al.
Publicado: (2020)

Active role of elongation factor G in maintaining the mRNA reading frame during translation
por: Peng, Bee-Zen, et al.
Publicado: (2019)

Dual use of GTP hydrolysis by elongation factor G on the ribosome
por: Cunha, Carlos E., et al.
Publicado: (2013)

Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation
por: Belardinelli, Riccardo, et al.
Publicado: (2021)

Gradual compaction of the nascent peptide during cotranslational folding on the ribosome
por: Liutkute, Marija, et al.
Publicado: (2020)

An mRNA-Derived Noncoding RNA Targets and Regulates the Ribosome
por: Pircher, Andreas, et al.
Publicado: (2014)

Thermodynamic control of −1 programmed ribosomal frameshifting
por: Bock, Lars V., et al.
Publicado: (2019)

Translational Control by Ribosome Pausing in Bacteria: How a Non-uniform Pace of Translation Affects Protein Production and Folding
por: Samatova, Ekaterina, et al.
Publicado: (2021)

Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance
por: Korniy, Natalia, et al.
Publicado: (2019)

The role of GTP hydrolysis by EF-G in ribosomal translocation
por: Rexroad, Gillian, et al.
Publicado: (2022)

Structural mechanism of GTPase-powered ribosome-tRNA movement
por: Petrychenko, Valentyn, et al.
Publicado: (2021)

Correlated conformational events in EF-G and the ribosome regulate translocation
por: Munro, James B., et al.
Publicado: (2010)

New insights into the enzymatic role of EF-G in ribosome recycling
por: Zhang, Dejiu, et al.
Publicado: (2015)

Altered tRNA dynamics during translocation on slippery mRNA as determinant of spontaneous ribosome frameshifting
por: Poulis, Panagiotis, et al.
Publicado: (2022)

Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA
por: Andreeva, Irena, et al.
Publicado: (2018)

Modulation and Visualization of EF‐G Power Stroke During Ribosomal Translocation
por: Yin, Heng, et al.
Publicado: (2019)

The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G)
por: Hirokawa, Go, et al.
Publicado: (2008)

Rejection of tmRNA·SmpB after GTP hydrolysis by EF-Tu on ribosomes stalled on intact mRNA
por: Kurita, Daisuke, et al.
Publicado: (2014)

Long-range signalling in activation of the translational GTPase EF-Tu
por: Rodnina, Marina V
Publicado: (2009)

Chemical and structural characterization of a model Post-Termination Complex (PoTC) for the ribosome recycling reaction: Evidence for the release of the mRNA by RRF and EF-G
por: Iwakura, Nobuhiro, et al.
Publicado: (2017)

EF-G catalyzed translocation dynamics in the presence of ribosomal frameshifting stimulatory signals
por: Kim, Hee-Kyung, et al.
Publicado: (2017)

Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation
por: Demo, Gabriel, et al.
Publicado: (2021)

Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP
por: Carbone, Christine E., et al.
Publicado: (2021)

Polysomes Bypass a 50-Nucleotide Coding Gap Less Efficiently Than Monosomes Due to Attenuation of a 5′ mRNA Stem–Loop and Enhanced Drop-off
por: O'Loughlin, Sinéad, et al.
Publicado: (2020)

Protocol to measure ribosome density along mRNA transcripts of Arabidopsis thaliana tissues using Ribo-seq
por: Vélez-Bermúdez, Isabel Cristina, et al.
Publicado: (2023)

Partitioning between recoding and termination at a stop codon–selenocysteine insertion sequence
por: Kotini, Suresh Babu, et al.
Publicado: (2015)

Mechanism of fusidic acid inhibition of RRF- and EF-G-dependent splitting of the bacterial post-termination ribosome
por: Borg, Anneli, et al.
Publicado: (2016)

The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation
por: Wieland, Maximiliane, et al.
Publicado: (2022)

What Are the Molecular Requirements for Protein Sliding along DNA?
por: Bigman, Lavi S., et al.
Publicado: (2021)

Outwitting EF-Tu and the ribosome: translation with d-amino acids
por: Achenbach, John, et al.
Publicado: (2015)

Timing of GTP binding and hydrolysis by translation termination factor RF3
por: Peske, Frank, et al.
Publicado: (2014)

Quantitative analysis of ribosome–mRNA complexes at different translation stages
por: Shirokikh, Nikolay E., et al.
Publicado: (2010)

Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation
por: Koripella, Ravi Kiran, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8e6bqad2qdc29tug7klo3ujqli