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The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

Cellular senescence is a stress response program characterized by a robust cell cycle arrest and the induction of a proinflammatory senescence-associated secretory phenotype (SASP) that is triggered through an unknown mechanism. Here, we show that, during oncogene-induced senescence (OIS), the Toll-...

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Detalles Bibliográficos
Autores principales: Hari, Priya, Millar, Fraser R., Tarrats, Nuria, Birch, Jodie, Quintanilla, Andrea, Rink, Curtis J., Fernández-Duran, Irene, Muir, Morwenna, Finch, Andrew J., Brunton, Valerie G., Passos, João F., Morton, Jennifer P., Boulter, Luke, Acosta, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551188/
https://www.ncbi.nlm.nih.gov/pubmed/31183403
http://dx.doi.org/10.1126/sciadv.aaw0254