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A Digestion-free Method for Quantification of Residual Host Cell DNA in rAAV Gene Therapy Products
Recombinant adeno-associated virus (rAAV) is a vector with increasing popularity in the field of gene therapy. Like other drug substances manufactured in cell lines, rAAV vectors are commonly contaminated with host cell DNA, and the levels must be carefully monitored. The current method for residual...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551374/ https://www.ncbi.nlm.nih.gov/pubmed/31194094 http://dx.doi.org/10.1016/j.omtm.2019.05.005 |